UK-Based Vesalic Limited Emerges from Stealth with Landmark Discovery of Potential Non-CNS Driver of Motor Neuron Diseases, including ALS, and Breakthrough Therapeutic and Diagnostic Opportunities
This groundbreaking discovery has revealed a systemic metabolic dysfunction that creates a toxic exosome cargo in ALS patients, which is carried to the CNS, where it binds to and damages neuronsVesalic is pioneering a novel therapeutic to intercept and neutralise these toxins, potentially slowing or halting progression of monogenic and sporadic forms of ALSIn addition, Vesalic has discovered a disease-specific alteration of the lipid composition in the membranes of exosomes circulating in the blood, and has developed a highly accurate biomarker-based technology to detect both monogenic and sporadic ALSBased on its novel biomarker discoveries, Vesalic is also applying its biomarker technology for other neurodegenerative diseases, including Alzheimer's and Parkinson's
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Gotterup tops Matsuyama in playoff to win Phoenix Open
Chris Gotterup won the PGA Tour Phoenix Open on Sunday, topping Hideki Matsuyama with a birdie at the first playoff hole as the Japanese major-winner found the water just moments after surrendering the outright lead at the 72nd hole.
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New Zealand's Christchurch mosque killer appeals conviction
A white supremacist who shot and killed 51 people at two New Zealand mosques in 2019 launched an appeal Monday seeking to overturn his conviction.
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Leonard's 41 leads Clippers over T-Wolves, Knicks cruise
Kawhi Leonard scored 41 points, grabbed eight rebounds and made four steals on Sunday to lead the Los Angeles Clippers in a lopsided 115-96 NBA victory at Minnesota.
Read moreVonn needs surgery on fracture after brutal end to Olympic dream
Lindsey Vonn needed surgery on her broken leg after she crashed out of the Winter Olympics downhill on Sunday to brutally end the American skiing great's improbable dream of a medal.
Read morePatriots-Seahawks Super Bowl approaches as politics swirl
Players and fans arrived Sunday for the biggest event in American sports as the New England Patriots face the Seattle Seahawks at the Super Bowl, where Bad Bunny will perform the half-time show in a tense political climate.
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Trump says China's Xi to visit US 'toward the end of the year'
US President Donald Trump has said he will host Chinese leader Xi Jinping at the White House late this year, as the world's top two economies look to reset ties marred by a roiling trade war.
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Real Madrid edge Valencia to stay on Barca's tail, Atletico slump
Kylian Mbappe scored his 23rd goal of the season in La Liga to help Real Madrid claim a battling 2-0 win at Valencia on Sunday and close the gap to leaders Barcelona to one point.
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Malinin keeps USA golden in Olympic figure skating team event
US star Ilia Malinin saw off a resurgent Japan with a pulsating routine to keep the Olympic team figure skating gold in American hands on Sunday.
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Lebanon building collapse toll rises to 9: civil defence
The death toll in a building collapse in the northern Lebanese city of Tripoli on Sunday climbed to nine, a civil defence official said -- the second such incident in weeks.
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